ABSTRACT
Hepatectomy is a common surgical procedure for hepatic surgeries, and due to its high complexity, the mortality rate after hepatectomy is as high as 30%. As one of the most common postoperative complications, posthepatectomy liver failure (PHLF) directly affects the disease-free survival and overall survival of patients after hepatectomy. Although there are great improvements in liver surgeries in the past ten years, PHLF cannot be avoided due to the condition and liver reserve function of patients before surgery. Although current techniques can significantly reduce the mortality rate of PHLF and bring more opportunities to patients, how to effectively evaluate the risk of PHLF and guide prevention and treatment strategies is still a major concern of liver surgeons. This article reviews the recent research on PHLF, including the definition, risk factors, preoperative evaluation, and prevention and treatment of PHLF, so as to provide a reference for reducing PHLF and performing effective treatment.